Perysinakis Iraklis
October 7, 2026 2026-10-07 10:49Perysinakis Iraklis
Perysinakis Iraklis
Assistant Professor of General Surgery and Surgical Oncology
Medical School, University of Crete, P.C. 70013 Heraklion, Crete
Iraklis Perysinakis is an Assistant Professor of General Surgery – Surgical Oncology at the School of Medicine, University of Crete.
He was born on 9 October 1983 in Heraklion, Crete, and graduated with distinction from the School of Medicine of the National and Kapodistrian University of Athens (NKUA) in 2007. He completed his specialty training in General Surgery at the 3rd Department of Surgery of the “G. Gennimatas” General Hospital of Athens in 2016. In 2017, as a scholar of the State Scholarships Foundation (IKY), he completed his doctoral thesis with distinction and was awarded a PhD by the Athens Medical School. That same year he passed the European Board of Surgery Qualification (EBSQ) examination and was awarded the title of Fellow of the European Board of Surgery (FEBS).
He has worked as a Consultant Surgeon in the 3rd Department of Surgery at the Hygeia Diagnostic and Therapeutic Centre of Athens, as a Locum Consultant in the Department of Surgery at the General Hospital of Rethymno, and later as a Consultant Surgeon (Grade B, Greek National Health System – ESY) at the General Hospital of Sitia. In November 2022 he was appointed Consultant Surgeon (Grade B, ESY) in the Department of Surgical Oncology at the University General Hospital of Heraklion. In April 2025 he moved to the United Kingdom as a fellow of the Hellenic Society of Coloproctology to train further in lower gastrointestinal surgery. There, he held a salaried post as Senior Clinical Fellow at St Thomas’ Hospital, London, for one year. In December 2025 he was elected Assistant Professor of General Surgery – Surgical Oncology at the School of Medicine, University of Crete.
His scientific work to date includes 41 articles published in Greek and international journals, more than 100 presentations at Greek and international conferences, invited lectures at Greek conferences, participation in research protocols, and authorship of books. He has attended postgraduate training courses, including advanced laparoscopic colorectal surgery courses in Strasbourg (IRCAD) and at Hygeia Hospital, Athens (CLASS course, Node Institute). He is a member of the Hellenic Surgical Society, the Hellenic Society of Endoscopic Surgery, the American College of Surgeons (FACS), the European Association for Endoscopic Surgery (EAES), and the Hellenic Society of Coloproctology. He is also on the UK Specialist Register for General Surgery (General Medical Council)
2025–2026: Senior Clinical Fellow in Colorectal Surgery, Gastrointestinal Medicine and Surgery, Lower GI Department, St Thomas’ Hospital, London, United Kingdom
2012–2016: PhD, National and Kapodistrian University of Athens, 2nd Department of Propaedeutic Surgery. Thesis: “Contribution to the Classification of Carcinoma of the Ampulla of Vater”
2010–2016: Specialty training in General Surgery, 3rd Department of Surgery, “G. Gennimatas” General Hospital of Athens
2001–2007: Degree in Medicine (MD), School of Medicine, National and Kapodistrian University of Athens
Colorectal cancer
Benign colorectal diseases
Inflammatory bowel disease (IBD)
1. A.V.Kyriakidis, I.Perysinakis, I.Alexandris, K.Athanasiou, Ch.Papadopoulos, I.Mpesikos. Parecoxib sodium in the treatment of postoperative pain after Lichtenstein tension-free mesh inguinal hernia repair. Hernia 2010 Feb;15(1):59-64.
2. A. V. Kyriakidis, P. Karydakis, G. Svoronos, I. Perysinakis, K. Athanasiou, Ch. Christakis. A 68-year Old Patient with Cholelithiasic Pancreatitis and three Anatomic Anomalies of the Pancreaticobiliary System. Hellenic Journal of Surgery 2010; 82: 1.
3. A.V.Kyriakidis, G.Karamalis, I.Perysinakis, I.Mpesikos, I.Vezyrgiannis, G.Androutsopoulos, N.Kazanas. Massive intestinal prolapse through vagina (Enterocele). Hellenic Journal of Surgery 2010; 82:2, 269-273.
4. A.V.Kyriakidis, I.Alexandris, E.Papoulia, K.Athanasiou, I.Perysinakis, M.Pyrgioti, D.Mpourganos. C-reactive protein: diagnostic aid in right lower quadrant abdominal pain. Ann Gastro 2010, 23(4):307-310.
5. A.V.Kyriakidis, S.Papanikolaou, I.Perysinakis, I.Vezyrgiannis, L.Xantzis, Ch.Papadopoylos, Ath.Zaharopoulos, G.Xenos. Intraabdominal injuries caused by migration of guide wire after intramedullary osteosynthesis in intertrochanteric hip fracture. Hellenic Journal of Surgery 2010; 82: 6, 397-400.
6. D.Georgiadou, I.Perysinakis, J.Spyridakis, D.Vaidakis, S.Avlonitis, A.Katopodi, G.N.Zografos. Intraoperative neuromonitoring of the recurrent laryngeal nerve: Initial experience. Hellenic Journal of Surgery 2011; 83:3.
7. Perysinakis I, Nixon A, Katopodi A, Tzirakis E, Georgiadou D, Avlonitis S, Margaris. I. Long term survival after right hemicolectomy and pancreatoduodenectomy for locally advanced colonic cancer: case report. IJSCR 2 (2011) 206– 207.
8. G.N.Zografos, N.Kopanakis, G.Vasiliades, H.Perysinakis, D.Vaidakis, S.Avlonitis, I. Margaris, I.Tsipras. Pancreatic Fistula Following Distal Pancreatectomy: How to Prevent. Hellenic Journal of Surgery 2012; 84: 6.
9. Perysinakis I, Katopodi A, Avlonitis S, Georgiadou D, Choreftaki T, Christopoulos G, Margaris I. Metastatic leiomyosarcoma of the intrapancreatic bile duct. J Korean Surg Soc. 2013 Jan; 84(1):66-69.
10. Perysinakis I, Marakaki C, Avlonitis S, Katseli A, Vassilatou E, Papanastasiou L, Piaditis G, Zografos GN. Laparoscopic adrenalectomy in patients with subclinical Cushing syndrome. SurgEndosc. 2013 Jun;27(6):2145-8. [IF=3.209]
11. P.Karydakis, A.V.Kyriakidis, G.Svoronos, I.Perysinakis, A.Mystakidis, N.Oiconomou, A.Fotopoulos, A.Roumeliotis, Ch.Christakis. Is low-anterior resection for rectal cancer equally efficient in the hands of non-expertised surgeons? Hellenic Journal of Surgery (2014) 86:1, 10-18.
12. Perysinakis I, Margaris I, Kouraklis G. Ampullary cancer – a separate clinical entity? Histopathology (2014); 64, 759-768. [IF=3.294]
13. Iraklis Perysinakis, Alexander Nixon, Ioannis Spyridakis, George Kakiopoulos, Charalampos Zorzos, Ilias Margaris. Primary intrahepatic malignant epithelioid mesothelioma. Int J Surg Case Rep. 2014; 5(12): 1098–1101.
14. G.N.Zografos, I.Perysinakis, E.Vassilatou. Subclinical Cushing’s syndrome: Current concepts and trends. Hormones (2014), 13(3):1-15.
15. G.N.Zografos, I.Perysinakis, E.Kyrodimou, E.Kassi, G.Kaltsas. Surgical treatment of potentially primary malignant adrenal tumors: an unresolved issue. Hormones (2015), 14(1):47-58
16. Iraklis Perysinakis, Spyridon Avlonitis, Despoina Georgiadou, Hercules Tsipras, Ilias Margaris. Five-year actual survival after pancreatoduodenectomy for pancreatic head cancer. ANZ J Surg. 2015 Mar; 85(3):183-6.
17. P. Karydakis, D. Semenov, A.Kyriakidis, Z. Osmanov, I.Perysinakis, E. Did-Zurabova, Y. Chekmasov, L. Karydakis, V. Kyriakidis. Laparoscopic management of perforated peptic ulcer: simple closure or something more? Open Journal of Gastroenterology, 2016, 6, 149-156.
18. Perysinakis I, Aggeli C, Kaltsas G, Zografos GN. Neoadjuvant therapy for advanced pancreatic neuroendocrine tumors: an emerging treatment modality? Hormones (Athens). 2016 Jan;15(1):15-2
19. Iraklis Perysinakis, Emilia Minaidou, Vasileia Leontara, Dimitrios Mantas, Georgios C.Sotiropoulos, Hercules Tsipras, George N.Zografos, Ilias Margaris, Gregory Kouraklis. Differential expression of β-catenin, EGFR, CK7, CK20, MUC1, MUC2 and CDX2 in intestinal and pancreatobiliary type ampullary carcinomas. Int J Surg Pathol. 2016 Aug; 25(1):31-40
20. Iraklis Perysinakis, Emilia Minaidou, Dimitrios Mantas, Georgios C.Sotiropoulos, Vasileia Leontara, Hercules Tsipras, George N.Zografos, Ilias Margaris, Gregory Kouraklis. Differentiation and prognostic markers in ampullary cancer: Role of p53, MDM2, CDX2, mucins and cytokeratins. Pathol Res Pract. 2016 Nov; 212(11):1039-1047. doi: 10.1016/j.prp.2016.09.004. Epub 2016 Sep 22.
21. M.Devetzi, V.Kosmidou, M.Vlassi, I. Perysinakis, C. Aggeli, T.Choreftaki, G.N.Zografos, A.Pintzas. Death receptor 5 (DR5) and a 5-gene apoptotic biomarker panel with significant differential diagnostic potential in colorectal cancer. Scientific Reports. 2016 Nov 9;6:36532. DOI: 10.1038/srep36532.[IF=4.525]
22. Kalliakmanis V, Perysinakis I, Koutsouvas K, Karras P, Margaris E, and Angelakis C. Massive intussusception caused by a solitary Peutz–Jeghers type hamartomatous polyp. The Annals of The Royal College of Surgeons of England 2018 100:4, e91-e93.
23. Kalliakmanis V, Koutsouvas K, Perysinakis I, Drakos-Galanis T, Margaris E. Gastric outlet obstruction by a large gallstone (Bouveret’s syndrome). Hellenic Journal of Surgery (2018) 90:3, 139-143
24. Chondros K, Perysinakis I, Kountourakis E, Chondros N. Which needle in which trocar? A mathematical-theoretical approach. Hellenic Journal of Surgery (2019) 91:3, 125-128
25. Perysinakis I, Pappis H, Kotsakou D. Cystic Duct Duplication: Report of a Case and Short Review of the Literature. Hellenic Journal of Surgery (2019) 91:4, 165-168
26. Perysinakis I, Pappis H, Margaris E. Current Controversies in Metabolic Surgery for Nonalcoholic Fatty Liver Disease. OBES SURG 29, 1058–1067 (2019). [IF=3.895]
27. Perysinakis, I. & Pappis, H.C. Burkitt Lymphoma of the Appendix with an Insidious Clinical Picture. Indian J Surg 81, 394–396 (2019).
28. Perysinakis I, Siligardou M, Savvides M, Papageorgiou K, Anyfantakis I, Vrentzou M, Papadaki P, Kalomenopoulou M, Stamatakis G. Hemocholecyst: Is surgery required? Indian J Surg, https://doi.org/10.1007/s12262-020-02227-6
29. Perysinakis, I., Aggeli, C., Kaltsas, G. et al. Adrenal-sparing surgery: current concepts on a theme from the past. Hormones (2020)19:317–327. https://doi.org/10.1007/s42000-020-00202-
30. Iraklis Perysinakis, Anastasia Spartinou, Savvides Maria, Mikela-Rafaella Siligardou, Lysandros Karydakis, Vladimiros Kyriakidis, Vasileios Panaritis, Alexandros Kyriakidis. Is There a Role for Color Doppler Ultrasonography in Acute Cholecystitis? Acta Medica Academica 2020;49(1):44-50
31. Perysinakis I, Spartinou A, Siligardou MR, Savvides M, Lianeris G, Stamatakis G. Pattern of road traffic injuries in the Rethymnon region, Crete, Greece: a secondary hospital-based study. Rural Remote Health. 2021 Aug;21(3):6529. doi: 10.22605/RRH6529. Epub 2021 Aug 2. PMID: 34339607.
32. Vassalou EE, Vardas K, Dimitriadis E, Perysinakis I. The Role of Imaging in the Pre- and Postoperative Evaluation of Inguinal Hernia. J Ultrasound Med. 2023 Oct;42(10):2425-2438. doi: 10.1002/jum.16241
33. Perysinakis I, Klontzas ME, Psaroudakis IG, Karantanas AH, de Bree E, Vassalou EE. Performance of Ultrasonography in the Diagnosis of Acute Colonic Diverticulitis. J Ultrasound Med 2024; 43:45–56. doi: 10.1002/jum.16333
34. Iraklis Perysinakis, Evangelia E. Vassalou. Non-traumatic lower abdominal pain: ultrasonographic and clinical differential diagnosis. Ultrasonography 2024;43:151-168
35. Iraklis Perysinakis, Kallirroi Spanou, Dimitrios Tamiolakis, Penelope Korkolopoulou, Georgios Stamatakis. Bowel Perforation and Peritonitis Caused by a Jejunal Leiomyoma. Hell J Surg. 2023 Oct-Dec;93(2):94–96
36. Perysinakis I, Vassalou EE, Saridakis G, Triantafyllou M, Christodoulou V, Triantafylla P, Papadaki E, De Bree E. Postoperative Bowel Obstruction as a Rare Complication of an Abdominal Drain. Ann Ital Chir. 2024;95(2):132-135
37. Perysinakis I, Saridakis G, Giannarakis M, et al. (April 24, 2024) Cocaine-Induced Chronic Bowel Ischemia Manifesting As Small Bowel Obstruction. Cureus 16(4): e58964. doi:10.7759/cureus.58964
38. Vassalou EE, Perysinakis I, Klontzas ME, de Bree E, Karantanas AH. Performance of thoracic ultrasonography compared with chest radiography for the detection of rib fractures using computed tomography as a reference standard. Skeletal Radiol. 2024 Mar 19. doi: 10.1007/s00256-024-04658-8. Epub ahead of print. PMID: 38499892.
39. Vassalou, E.E., Perysinakis, I., Michelakis, D., Karantanas, A., de Bree, E.. Multidetector CT of the postoperative sigmoid colon and rectum: Imaging of common complications. Egypt J Radiol Nucl Med 55, 217 (2024).
40. Evangelia E. Vassalou, Iraklis Perysinakis, Eelco de Bree, Maria Raissaki. Thoracic Ultrasound in Pediatric Chest Trauma. Beyond the Basics. J Ultrasound Med 2025; 9999:1–17
41. Perysinakis I, Karona P, Christodoulou V, et al. (May 11, 2025) Prophylactic Pelvic Drainage of Extraperitoneal Rectal Anastomoses: A Friend or a Foe?. Cureus 17(5): e83905. doi:10.7759/cureus.83905
42. Michelakis D, Perysinakis I, Schizas D, et al. (July 12, 2026) Extended Lymphadenectomy for Right-Sided Colon Cancer: A Systematic Review and Narrative Synthesis of Evidence, Technique, and Patient Selection. Cureus 18(7): e112512. doi:10.7759/cureus.112512
1. Hellenic Surgical Society
2. Hellenic Society of Endoscopic Surgery
3. General Medical Council (Fully registered medical practitioner with specialist registration with a license to practice)
4. Fellow of the European Board of Surgery – General Surgery
5. Associate Fellow member of the American College of Surgeons
6. Heraklion Medical Association
7. Hellenic Bariatric Surgery Society
8. European Association of Endoscopic Surgery
9. European Society of Coloproctology
