The unit supports comparative genomic and proteomic analyses from an evolutionary perspective.

These analyses aim to:

• Identify conserved genes
• Infer functional relationships
• Investigate the evolutionary mechanisms shaping biological systems across species

Analytical capabilities include:

• Comparative genome analysis and evolutionary studies to identify conserved genomic regions and lineage-specific adaptations
• Identification and analysis of protein families, including ortholog clustering and protein domain architecture analysis
• Phylogenetic analysis for reconstructing evolutionary relationships among genes, proteins, and species
• Gene neighborhood analysis to investigate conserved genomic organization and gene context across multiple genomes
• Phylogenetic profiling to identify functionally related genes based on shared patterns of presence or absence across large collections of genomes
• Detection of gene and protein fusion events across genomes, providing evidence for functional associations between proteins and biological pathways

These approaches facilitate the discovery of conserved functional modules, prediction of gene function, and investigation of molecular evolution across organisms.