Kritsotakis Evangelos

Kritsotakis Evangelos

Κριτσωτάκης Ευάγγελος - Kritsotakis Evangelos

Kritsotakis Evangelos

Associate Professor of Biostatistics

Phone number +30.2810.39.4619

Laboratory of Biostatistics

Medical School, University of Crete, P.C. 71003 Heraklion, Crete

Evangelos Kritsotakis joined the School of Medicine at the University of Crete as an Associate Professor of Biostatistics in December 2018. Before this, he held a post as a tenured Lecturer (Assistant Professor) in Epidemiology and Medical Statistics at the University of Sheffield, UK (2014-2018), where he maintained an honorary position of Senior Lecturer at the School of Medicine and Population Health until December 2024.

His first degree was in mathematics (University of Crete, Greece, 1998), followed by a Master’s in statistics and operational research (University of Essex, UK, 2000). He completed training in applied epidemiology at the Rollins School of Public Health, Emory University, and the US Centers for Disease Control and Prevention (Atlanta, USA, 2005). He was awarded a PhD from the Faculty of Medicine at the University of Crete in 2007.

Dr Kritsotakis is an elected Chartered Statistician of the Royal Statistical Society, UK, and an elected Fellow of the Higher Education Academy, UK. He is a Senior Associate Editor for the journal ‘Public Health’ (Royal Society for Public Health, UK) and an Associate Editor for the journal ‘npj Primary Care Respiratory Medicine’ (International Primary Care Respiratory Group). He is an active member of the International Society for Clinical Biostatistics, serving on the ISCB Student Conference Award Committee. He is a statistical reviewer for journals in the Lancet group and conducts ad-hoc reviews of research papers in numerous reputable medical research journals. He was recognised as one of the top reviewers in 2020 for the journal “Clinical Microbiology and Infection” of the European Society of Clinical Microbiology and Infectious Diseases. He has significant experience as an expert/reviewer in national and international (European Commission) large-scale research funding evaluations.

Dr Kritsotakis’ academic teaching includes introductory and advanced modules in Medical Statistics, Epidemiology, and Research Methodology in undergraduate medicine, and postgraduate programmes in Public Health and the Surgical Sciences. He supervises master’s and doctoral students doing applied and/or methodological research in these fields at the University of Crete. He also teaches the core module Survival Data Analysis in the MSc in Biostatistics and Health Data Science at the University of Athens.

o 2017 PGCert Learning & Teaching in Higher Education, School of Education, Faculty of Social Sciences, University of Sheffield, UK.

o 2007 PhD, School of Medicine, Faculty of Health Sciences, University of Crete, GR. Dissertation topic: “Development of an antibiotic use surveillance system, statistical investigation of the relationship between antibiotic consumption and antimicrobial resistance, and implementation of evidence-based antibiotic policies in the district general hospitals of Crete” (supervisor: Dr Achilleas Gikas).

o 2005 PGCert International Course in Applied Epidemiology, Rollins School of Public Health, Emory University and CDC, USA. http://web1.sph.emory.edu/epicourses/internat.htm

o 2000 MSc Statistics & Operational Research, Department of Mathematical Sciences, Faculty of Science and Health, University of Essex, UK. Mater’s dissertation topic: “Statistical issues in credit scoring classification” (supervisor: Dr H.G. Li).

o 1998 BSc (Hons) Mathematics, Department of Mathematics, School of Sciences & Engineering, University of Crete, GR. Undergraduate dissertation topic “Applications of the Theory of Modules in Group Theory and Linear Algebra” (supervisor: Dr Alexis Kouvidakis)

Evangelos Kritsotakis has over 15 years of experience in the design, data analysis, and reporting of clinical and epidemiological research studies in acute care hospitals and other healthcare settings. His published research comprises mainly collaborative applied and translational studies, with long-term interdisciplinary work on the clinical epidemiology of healthcare-associated infections, multi-drug-resistant pathogenic bacteria, and antimicrobial drugs. Acknowledging his research contribution, the Society for Healthcare Epidemiology of America awarded me the William Jarvis Award in 2009. During 2010–12 and 2015–17, he joined the works of ECDC’s European Network for Healthcare-associated Infection Surveillance (HAI-Net). He actively contributed as a member of the National Coordination Team to design and implement the first two national prevalence studies of healthcare-associated infections and antimicrobial use in acute-care hospitals in Greece. Dr Kritsotakis’ experience includes conducting prognostic and aetiologic clinical studies, developing and validating clinical prediction models (for diagnostic and prognostic research), quasi-experimental and time-series studies for evaluating population-based interventions, epidemiological cohort studies, complex sample surveys, systematic reviews, and meta-analyses.

Fields of research activity:
• Design and analysis of prognostic clinical studies using survival analysis methods
• Development, validation and application of clinical prediction models and algorithms
• Intervention evaluation using quasi-experimental designs and time series models
• Systematic reviews and meta-analyses of epidemiological studies
• Interdisciplinary research in healthcare epidemiology to control multi-drug-resistant bacterial infections

https://www.ncbi.nlm.nih.gov/myncbi/evangelos.kritsotakis.1/bibliography/public/

https://scholar.google.gr/citations?user=bEsrTzwAAAAJ&hl=en

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Selected publications (last 5 years):
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1. Durojaiye OC and Kritsotakis EI. Evaluation of health-related quality of life in patients receiving outpatient parenteral antimicrobial therapy (OPAT) in a UK setting. Expert Rev Anti Infect Ther 2024; PMID: 38511820.

2. Daskalakis II, Kritsotakis EI, Karantanas AH, Kontakis GM, Bastian JD, Tosounidis TH. Application of an in-hospital, surgeon-led anti-osteoporotic medication algorithm in patients with hip fractures improves persistence to medication and can prevent the second fragility fracture. Arch Orthop Trauma Surg 2024; 144(2):683-692. PMID: 38044337.

3. Karakonstantis S, Rousaki M, Vassilopoulou L, Kritsotakis EI. Global prevalence of cefiderocol non-susceptibility in Enterobacterales, Pseudomonas aeruginosa, Acinetobacter baumannii, and Stenotrophomonas maltophilia: a systematic review and meta-analysis. Clinical Microbiology and Infection 2024;30(2):178-188. PMID: 37666449.

4. Kokkinakis S, Kritsotakis EI, [37 more co-authors], Lasithiotakis K. Development and internal validation of a clinical prediction model for serious complications after emergency laparotomy. European Journal of Trauma and Emergency Surgery 2024;50(1):283-293. PMID: 37648805.

5. Durojaiye OC, Cole J, Kritsotakis EI. Risk of venous thromboembolism in outpatient parenteral antimicrobial therapy (OPAT): a systematic review and meta-analysis. International Journal of Antimicrobial Agents 2023; 62(3): 106911. PMID: 37422098.

6. Kokkinakis S, Kritsotakis EI, Lasithiotakis K. Artificial Intelligence in Surgical Risk Prediction. Journal of Clinical Medicine 2023; 12(12):4016. PMID: 37373709.

7. Bolikas E, Astrinaki E, Panagiotaki E, Vitsaxaki E, Saplamidou S, Drositis I, Stafylaki D, Chamilos G, Gikas A, Kofteridis DP, Kritsotakis EI. Impact of SARS-CoV-2 preventive measures against healthcare-associated infections from multidrug-resistant ESKAPEE pathogens: a two-center natural quasi-experimental study in Greece. Antibiotics 2023; 12(7):1088. PMID: 37508184.

8. Spernovasilis N, Kritsotakis EI, Mathioudaki A, Vouidaski A, Spanias C, Petrodaskalaki M, Ioannou P, Chamilos G, Kofteridis DP. A carbapenem-focused antimicrobial stewardship program implemented during the COVID-19 pandemic in a setting of high endemicity for multidrug-resistant Gram-negative bacteria. Journal of Antimicrobial Chemotherapy 2023; 78(4):1000-1008. PMID: 36790896.

9. Kokkinakis S, Kritsotakis EI, [38 more co-authors], Lasithiotakis K. Prospective multicenter external validation of postoperative mortality prediction tools in patients undergoing emergency laparotomy. Journal of Trauma and Acute Care Surgery 2023; 94(6):847-856. PMID: 36726191.

10. Kritsotakis EI, Lagoutari D, Mihaillelis E, Georgakakis I, Gikas A. Burden of multidrug and extensively drug-resistant ESKAPEE pathogens in a secondary acute care setting in Greece. Epidemiology and Infection 2022; 150:e170. PMID: 36148865.

11. Durojaiye OC, Morgan R, Chelaghma N, Kritsotakis EI. Clinical predictors of outcome in patients with infective endocarditis receiving outpatient parenteral antibiotic therapy (OPAT). Journal of Infection 2021; 83(6):644-649. PMID: 34614400.

12. Karakonstantis S and Kritsotakis EI. Systematic review and meta-analysis of the proportion and associated mortality of polymicrobial (vs monomicrobial) pulmonary and bloodstream infections by Acinetobacter baumannii complex. Infection 2021; 49(6):1149-1161. PMID: 34260054.

13. Durojaiye OC, Morgan R, Chelaghma N, Palit J, Keil C, Omer R, Cartwright K, Kritsotakis EI. External validity and clinical usefulness of a risk prediction model for 30-day unplanned hospitalisation in patients receiving outpatient parenteral antimicrobial therapy. Journal of Antimicrobial Chemotherapy 2021; 76: 2204-2212. PMID: 33895844.

14. Karakonstantis S, Gikas A, Astrinaki E, Kritsotakis EI. Excess mortality due to pandrug-resistant Acinetobacter baumannii infections in hospitalized patients. Journal of Hospital Infection 2020; 106(3):447-53.PMID: 32927013.

15. Kritsotakis EI, Groves-Kozhageldiyeva A. A systematic review of the global seasonality of infections caused by Acinetobacter species in hospitalized patients. Clinical Microbiology and Infection 2020; 26(5):553-562. PMID: 31586659.

• International Society for Clinical Biostatistics (ISCB) https://iscb.international/
• Royal Statistical Society (RSS) https://rss.org.uk/
• Royal Society for Public Health (RSPH) https://www.rsph.org.uk/
• Higher Education Academy (AdvanceHE) https://www.advance-he.ac.uk/
• European Society of Clinical Microbiology and Infectious Diseases https://www.escmid.org/

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