-Μελέτη της επίδρασης των εμβολιασμών και του είδους των χορηγουμένων εμβολίων στην βρεφική και νηπιακή ηλικία στην επίπτωση της ατοπίας και του άσθματος.
– Μέτρηση των επιπέδων του βρογχικού και κυψελιδικού εκπνεομένο ΝΟ με τη μέθοδο των πολλαπλών ροών σε παιδιά με άσθμα, αλ. ρινίτιδα για την πρόγνωση παροξυσμών.
-Μελέτη των επιπέδων του βρογχικού και κυψελιδικού εκπνεομένο ΝΟ με τη μέθοδο των πολλαπλών ροών σε παιδιά με σακχαρώδη διαβήτη και συσχέτιση με την μικροαγγειοπάθεια.
– Πρόγνωση επιμονής στην σχολική ηλικία του άσθματος παιδιών προσχολικής ηλικίας με τη χρήση ΑΙ και νευρωνικών κυκλωμάτων.
-Μελέτη της επίδρασης της κλιματικής αλλαγής στον έλεγχο της νόσου παιδιών με βρογχικό άσθμα και αλλεργική ρινίτιδα.
-Νέες μέθοδοι σπιρομέτρησης σε παιδιά προσχολικής ηλικίας.

Δημοσιεύσεις σε ελληνικά επιστημονικά περιοδικά: 6
Δημοσιεύσεις σε ξενόγλωσσα επιστημονικά περιοδικά: 58
(51 δημοσιεύσεις PubMed, 7 δημοσιεύσεις Scopus)
Άθροισμα συντελεστών απήχησης περιοδικών PubMed (I F) :303,73
Μέσος όρος συντελεστή απήχησης περιοδικών PubMed (IF) : 6
H index: 21
Σύνολο Αναφορών:1217
Πρώτος συγγραφέας σε περιοδικά με υψηλό συντελεστή απήχησης: 4 (Lancet Respir Med. IF 76,2, ERJ (2 άρθρα) IF 24,9, Am J Respir Crit Care Med IF 24,7)

1. Hillson K, Fontanella S, Almeida H, Pavlou B, Lajunen K, Irving S, Testa I, Bingham Y, Oritz KM, Lacbay S, Hay S, Gore M, Scotney E, Paraskakis E, Sonnappa S, Fleming L, Bush A, Saglani S. Point-of-Care Blood Eosinophils to Predict Preschool Wheeze Attacks. Allergy. 2025 Apr;80(4):1038-1046.
2. Boura D, Spanakis M, Markakis G, Notas G, Lionis C, Tzanakis N, Paraskakis E. Exploring the Relationship between Wind Patterns and Hospital Admissions Due to Respiratory Symptoms in Children. Children (Basel). 2024 Jun 12;11(6):717. doi: 10.3390/children11060717. PMID: 38929296; PMCID: PMC11201383.
3. Paraskakis E, Bush A. Dupilumab: VOYAGE of discovery leading to a further EXCURSION. Lancet Respir Med. 2023 Nov 10:S2213-2600(23)00337-5. doi: 10.1016/S2213-2600(23)00337-5. Epub ahead of print. PMID: 37956681.
4. Sarikloglou E, Fouzas S, Paraskakis E. Prediction of Asthma Exacerbations in Children. J Pers Med. 2023 Dec 22;14(1):20. doi: 10.3390/jpm14010020. PMID: 38248721; PMCID: PMC10820562.
5. Goniotakis I, Perikleous E, Fouzas S, Steiropoulos P, Paraskakis E. A Clinical Approach of Allergic Rhinitis in Children. Children (Basel). 2023 Sep 19;10(9):1571. doi: 10.3390/children10091571. PMID: 37761533; PMCID: PMC10528841.
6. Perikleous EP, Gkentzi D, Bertzouanis A, Paraskakis E, Sovtic A, Fouzas S. Antibiotic Resistance in Patients with Cystic Fibrosis: Past, Present, and Future. Antibiotics (Basel). 2023 Jan 20;12(2):217. doi: 10.3390/antibiotics12020217. PMID: 36830128; PMCID: PMC9951886.
7. Perikleous EP, Fouzas S, Michailidou M, Patsourou A, Tsalkidis D, Steiropoulos P, Nena E, Chatzimichael A, Paraskakis E. Association between History of Prolonged Exclusive Breast-Feeding and the Lung Function Indices in Childhood. Children (Basel). 2022 Nov 8;9(11):1708. doi: 10.3390/children9111708. PMID: 36360436; PMCID: PMC9688515.
8. Perikleous EP, Steiropoulos P, Nena E, Paraskakis E. Biologic Therapies in Pediatric Asthma. J Pers Med. 2022 Jun 18;12(6):999. doi: 10.3390/jpm12060999. PMID: 35743783; PMCID: PMC9224795.
9. Kakatsaki I, Vergadi E, Paraskakis E, Galanakis E. Attitudes of junior healthcare professionals towards mandatory vaccination. Vaccine. 2022 Apr 1;40(15):2247-2250. doi: 10.1016/j.vaccine.2022.03.010. Epub 2022 Mar 10. PMID: 35282926.
10. Paraskakis E, Sarikloglou E, Fouzas S, Steiropoulos P, Tsalkidis A, Bush A. Improved prediction of asthma exacerbations by measuring distal airway inflammation. Eur Respir J. 2022 Jan 27:2101684. doi: 10.1183/13993003.01684-2021. Epub ahead of print. PMID: 35086836.
11. Perikleous E, Fouzas S, Karageorgiou A, Steiropoulos P, Nena E, Chatzimichael A, Tsalkidis A, Paraskakis E. Association of breastfeeding with tidal breathing analysis in infants with bronchiolitis. World J Clin Pediatr. 2021 Nov 9;10(6):168-176. doi: 10.5409/wjcp.v10.i6.168. PMID: 34868893; PMCID: PMC8603642.
12. Kostopoulou E, Sinopidis X, Gidaris D, Karantaglis N, Cassimos D, Gkentzi D, Karatza AA, Paraskakis E, Jelastopulu E, Dimitriou G, Fouzas S. Parents under siege: the psychological impact of COVID-19 outbreak on children’s caregivers. Swiss Med Wkly. 2021 Aug 13;151(31-32). doi: 10.4414/SMW.2021.w30012. PMID: 34407364.
13. Fouzas S, Gidaris D, Karantaglis N, Opsimos H, Alexopoulos EI, Douros K, Kirvassilis F, Paraskakis E, Anthracopoulos MB, Marangos M, Tsanakas I; Hellenic Pediatric Respiratory Society. Pediatric Pulmonary Function Testing in COVID-19 Pandemic and Beyond. A Position Statement From the Hellenic Pediatric Respiratory Society. Front Pediatr. 2021 May 21;9:673322. doi: 10.3389/fped.2021.673322. PMID: 34095031; PMCID: PMC8175853.
14. Paraskakis E, Froudarakis M, Tsalkidou EA, Deftereos S, Sarris G, Tsalkidis A. An eight-year-old girl with tracheal mass treated as a difficult asthma case. J Asthma. 2021 Dec;58(12):1689-1693. doi: 10.1080/02770903.2020.1825730. Epub 2020 Sep 29. PMID: 32991249.
15. Perikleous E, Tsalkidis A, Bush A, Paraskakis E. Coronavirus global pandemic: An overview of current findings among pediatric patients. Pediatr Pulmonol. 2020 Dec;55(12):3252-3267. doi: 10.1002/ppul.25087. Epub 2020 Oct 7. PMID: 32965785; PMCID: PMC7646267.
16. Protopapas AA, Vradelis S, Karampitsakos T, Steiropoulos P, Chatzimichael A,Paraskakis E. Elevated Levels of Alveolar Nitric Oxide May Indicate Presence of Small Airway Inflammation in Patients with Inflammatory Bowel Disease. Lung. 2019;197(5):663-670.

17. Perikleous E, Steiropoulos P, Nena E, Iordanidou M, Tzouvelekis A,
Chatzimichael A, Paraskakis E. Association of Asthma and Allergic Rhinitis With Sleep-Disordered Breathing in Childhood. Front Pediatr. 2018 Sep 11;6:250. doi:10.3389/fped.2018.00250. eCollection 2018.
18. Spyroglou II, Spöck G, Rigas AG, Paraskakis EN. Evaluation of Bayesian classifiers in asthma exacerbation prediction after medication discontinuation. BMC Res Notes. 2018;11(1):522.
19. Perikleous E, Steiropoulos P, Tzouvelekis A, Nena E, Koffa M, Paraskakis E. DNA Methylation in Pediatric Obstructive Sleep Apnea: An Overview of Preliminary Findings. Front Pediatr. 2018;6:154.
20. Perikleous EP, Steiropoulos P, Paraskakis E, Constantinidis TC, Nena E. E-Cigarette Use Among Adolescents: An Overview of the Literature and Future Perspectives. Front Public Health. 2018;6:86.
21. Fotopoulou M, Iordanidou M, Vasileiou E, Trypsianis G, Chatzimichael A,Paraskakis E. A short period of breastfeeding in infancy, excessive house cleaning, absence of older sibling, and passive smoking are related to more severe atopic dermatitis in children. Eur J Dermatol. 2018;28(1):56-63.
22. Karampitsakos T, Protopapas A, Gianoloudi M, Papadopoulos VP, Bouros D, Chatzimichael A, Paraskakis E. The effect of bronchodilation and spirometry on fractional exhaled nitric oxide (FeNO50), bronchial NO flux (JawNO) and alveolar NO concentration (C(A)NO) in children and young adults. J Asthma. 2018;55(8):882-889.
23. Iordanidou M, Loukides S, Paraskakis E. Asthma phenotypes in children and stratified pharmacological treatment regimens. Expert Rev Clin Pharmacol. 2017;10(3):293-303.
24. Iordanidou M, Paraskakis E, Tavridou A, Chatzimichael A, Manolopoulos VG.Endothelial nitric oxide synthase gene polymorphisms are associated with sensitization to seasonal aeroallergens in asthmatic children. World J Pediatr. 2017;13(1):34-40.
25. Paraskakis E, Vergadi E, Chatzimichael A, Bush A. The Role of Flow-Independent Exhaled Nitric Oxide Parameters in the Assessment of Airway Diseases. Curr Top Med Chem. 2016;16(14):1631-42.
26. Iordanidou M, Paraskakis E, Giannakopoulou E, Tavridou A, Gentile G, Borro M, Simmaco M, Chatzimichael A, Bush A, Manolopoulos VG. Vitamin D Receptor ApaI a Allele Is Associated with Better Childhood Asthma Control and Improvement in Ability for Daily Activities. OMICS. 2014;18(11):673-81.
27. Fouka E, Lamprianidou E, Arvanitidis K, Filidou E, Kolios G, Miltiades P, Paraskakis E, Antoniadis A, Kotsianidis I, Bouros D. Low-Dose Clarithromycin Therapy Modulates Th17 Response In Non-Cystic Fibrosis Bronchiectasis Patients.Lung. 2014;192(6):849-55.
28. Stakos DA, Papaioannou HI, Angelidou I, Mantadakis E, Paraskakis E, TsigalouC, Chatzimichael A. Plasma leptin and adiponectin concentrations correlate with cardiometabolic risk and systemic inflammation in healthy, non-obese children. J Pediatr Endocrinol Metab. 2013:1-8.
29. Tsakiris A, Iordanidou M, Paraskakis E, Tsalkidis A, Rigas A, Zimeras S,Katsardis C, Chatzimichael A. The presence of asthma, the use of inhaled steroids, and parental education level affect school performance in children.Biomed Res Int. 2013;2013:762805
30. Rallis D, Spoulou V, Theodoridou M, Critselis E, Michailidou E, Kavaliotis J, Roilides E, Katragou A, Galanakis E, Triga M, Krokidas G, Tzoufi M, Spala G,Dikaiakou E, Paraskakis E, Syrogiannopoulos G, Papaventsis D, Tsolia MN. Current epidemiology of childhood tuberculous meningitis in Greece: a 10-year population-based study. Int J Tuberc Lung Dis. 2013;17(6):847-8
31. Chatzimichail E, Paraskakis E, Sitzimi M, Rigas A. An intelligent systemapproach for asthma prediction in symptomatic preschool children. Comput Math Methods Med. 2013;2013:240182.
32. Iordanidou M, Paraskakis E, Tavridou A, Paschou P, Chatzimichael A,Manolopoulos VG. G894T polymorphism of eNOS gene is a predictor of response to combination of inhaled corticosteroids with long-lasting β2-agonists in asthmatic children. Pharmacogenomics. 2012;13(12):1363-72.
33. Paraskakis E, Vergadi E, Chatzimichael A, Bouros D. Current evidence for the management of paediatric parapneumonic effusions. Curr Med Res Opin. 2012;28(7):1179-92.
34. Yanai K, Rogala B, Chugh K, Paraskakis E, Pampura AN, Boev R. Safety considerations in the management of allergic diseases: focus on antihistamines.Curr Med Res Opin. 2012;28(4):623-42.
35. Katotomichelakis M, Anastassakis K, Gouveris H, Tripsianis G, Paraskakis E,Maroudias N, Danielides V. Clinical significance of Alternaria alternate sensitization in patients with allergic rhinitis. Am J Otolaryngol. 2012;33(2):232-8.
36. Tsalkidis A, Vaos G, Gardikis S, Kambouri K, Tripsianis G, Mantadakis E,Paraskakis E, Chatzimicael A. Acute poisoning among children admitted to a regional university hospital in Northern Greece. Cent Eur J Public Health. 2010;18(4):219-23. 21361107.
37. Lialiaris T, Polyzou A, Mpountoukas P, Tsiggene A, Kouskoukis A, Pouliliou S,Paraskakis E, Tentes I, Trypsianis G, Chatzimichail A. Chromosome instability on children with asthma. J Asthma. 2009;46(8):841-4.
38. Thomou C, Paraskakis E, Neofytou E, Kalmanti M, Siafakas NM, Tzortzaki EG.Acquired somatic mutations in the microsatellite DNA, in children with bronchial asthma. Pediatr Pulmonol. 2009;44(10):1017-24.
39. Paraskakis E, Ntouros T, Ntokos M, Siavana O, Bitsori M, Galanakis E. Siesta and sleep patterns in a sample of adolescents in Greece. Pediatr Int. 2008;50(5):690-3.
40. Spathopoulos D, Paraskakis E, Trypsianis G, Tsalkidis A, Arvanitidou V, Emporiadou M, Bouros D, Chatzimichael A. The effect of obesity on pulmonary lung function of school aged children in Greece. Pediatr Pulmonol. 2009;44(3):273-80.
41. Mantadakis E, Tsalkidis A, Paraskakis E, Papadopoulou-Legbelou K, Varlamis G, Evangeliou A, Chatzimichael A. Anticonvulsant hypersensitivity syndrome closely mimicking Kawasaki disease. BMJ Case Rep. 2009;2009. doi:pii: bcr10.2008.1076. 10.1136/bcr.10.2008.1076. Epub 2009 May 25.
42. Katzilakis N, Paraskakis E, Mantadakis E, Stiakaki E, Kalmanti M. Bronchial asthma and acute lymphoblastic leukemia in childhood. Pediatr Pulmonol. 2008;43(2):206.
43. Suri R, Paraskakis E, Bush A. Alveolar, but not bronchial nitric oxide production is elevated in cystic fibrosis. Pediatr Pulmonol. 2007;42(12):1215-21.
44. Paraskakis E, Zihlif N, Bush A. Nitric oxide production in PCD: possible evidence for differential nitric oxide synthase function. Pediatr Pulmonol. 2007 ;42(10):876-80.
45. Makris D, Paraskakis E, Korakas P, Karagiannakis E, Sourvinos G, Siafakas NM, Tzanakis N. Exhaled breath condensate 8-isoprostane, clinical parameters,radiological indices and airway inflammation in COPD. Respiration.2008;75(2):138-44.
46. Paraskakis E, Brindicci C, Fleming L, Krol R, Kharitonov SA, Wilson NM, Barnes PJ, Bush A. Measurement of bronchial and alveolar nitric oxide production in normal children and children with asthma. Am J Respir Crit Care Med. 2006;174(3):260-7
47. Zihlif N, Paraskakis E, Tripoli C, Lex C, Bush A. Markers of airway inflammation in primary ciliary dyskinesia studied using exhaled breath condensate. Pediatr Pulmonol. 2006 Jun;41(6):509-14.
48. Zihlif N, Paraskakis E, Lex C, Van de Pohl LA, Bush A. Correlation betweencough frequency and airway inflammation in children with primary ciliary dyskinesia. Pediatr Pulmonol. 2005 Jun;39(6):551-7.
49. Paraskakis E, Sourvinos G, Passam F, Tzanakis N, Tzortzaki EG, Zervou M,Spandidos D, Siafakas NM. Microsatellite DNA instability and loss of heterozygosity in bronchial asthma. Eur Respir J. 2003;22(6):951-5.
50. Mamoulakis D, Galanakis E, Bicouvarakis S, Paraskakis E, Sbyrakis S.Epidemiology of childhood type I diabetes in Crete, 1990-2001. Acta Paediatr.2003;92(6):737-9.
51. Bitsori M, Galanakis E, Paraskakis E, Papadakis CE, Kokori H, Sbyrakis S.Mucus plugging as a cause of acute lobar overdistension. Pediatr Emerg Care. 2001;17(1):38-9.
52. Chatzimichail, E., Paraskakis, E., & Rigas, A. (2013). An evolutionary two-objective genetic algorithm for asthma prediction. Paper presented at the Proceedings – UKSim 15th International Conference on Computer Modelling and Simulation, UKSim 2013, 90-94.
53. Chatzimichail, E., Paraskakis, E., Sitzimi, M., & Rigas, A. (2011). Predicting the long-term outcome of preschool children with asthma symptoms. Paper presented at the 2011 E-Health and Bioengineering Conference, EHB 2011
54. Chatzimichail, E., Rigas, A., Paraskakis, E., & Chatzimichail, A. (2010). Diagnosis of asthma severity using artificial neural networks. Paper presented at the IFMBE Proceedings, 29 600-603.
55. Chatzimichail, E. A., Rigas, A. G., & Paraskakis, E. N. (2010). An artificial intelligence technique for the prediction of persistent asthma in children. Paper presented at the Proceedings of the IEEE/EMBS Region 8 International Conference
56. Spyroglou, I.I., Chatzimichail, E.A., Paraskakis, E.N., Rigas, A.G. A comparison of different ridge parameters in an asthma persistence prediction model. International Journal of Biology and Biomedical Engineering 2016 ;10: 1-9
57. Spyroglou, I.I., Chatzimichail, E.A., Spanou, E.N., Paraskakis, E.N., Rigas, A.G. Evaluation of a prediction model based on ridge regression for asthma persistence in preschool children. International Journal of Mathematical Models and Methods in Applied Sciences 2015;9:581-591
58. A bayesian logistic regression approach in asthma persistence prediction.Spyroglou, I.I , Spöck, G. , Chatzimichail, E.A. , Rigas, A.G. , Paraskakis, E. Epidemiology Biostatistics and Public Health2018;15(1): e12777-1-e12777-14

Ελληνική Παιδιατρική Εταιρεία
European Respiratory Society
General Medical Council UK
Τακτικό μέλος της Ελλανικής Παιδοπνευμονολογικής Εταιρείας