Tα κύρια επιστημονικά μου ενδιαφέροντα είναι στην Κλινική Μικροβιολογία και τη Μικροβιολογία Δημόσιας Υγείας, με στόχο την παροχή αξιόπιστων εργαστηριακών δεδομένων, τόσο σε επίπεδο ασθενούς όσο και πληθυσμού, για τη λήψη κλινικών αποφάσεων και μέτρων Δημόσιας Υγείας αντίστοιχα. Από το 2009 έως και σήμερα ασχολούμαι με τη μελέτη και τον τρόπο διασποράς των μηχανισμών αντοχής σε αντιβιοτικά κλινικών και περιβαλλοντικών στελεχών μικροβίων. Επιπλέον, με τη συστηματική εφαρμογή μεθόδων μοριακής βιολογίας για τη διάγνωση λοιμωδών νοσημάτων τη διερεύνηση συρροών και επιδημικών εξάρσεων λοιμώξεων από διάφορα μικροβιακά παθογόνα και την εργαστηριακή επιδημιολογική επιτήρηση λοιμωδών νοσημάτων μέσω σύγχρονων μεθόδων μοριακής τυποποίησης και γονιδιωματικής ανάλυσης.

List of publications

1. Mortality due to carbapenem-resistant Acinetobacter baumannii bacteraemia: author’s response. Karakonstantis S, Kritsotakis EI, Tziolos EN, Tryfinopoulou K, Kofteridis DP. Clinical Microbiology and InfectionOpen source preview, 2025, 31(9), pp. 1601–1602
2. A Retrospective Cohort Study of Leptospirosis in Crete, Greece. Ioannou P, Pendondgis M, Kampanieri E…Tryfinopoulou K, Kofteridis D. Tropical Medicine and Infectious Disease. 2025, 10(8), 209
3. Mortality due to carbapenem-resistant Acinetobacter baumannii bacteraemia: a five-year cohort study in intensive care patients. Karakonstantis S, et al. Among authors: Tryfinopoulou K. Clin Microbiol Infect. 2025. PMID: 39978636
4. Limited impact of colistin resistance on mortality of intensive care patients with carbapenem-resistant bacteraemia. Tziolos RN, et al. Among authors: Tryfinopoulou K. J Hosp Infect. 2024.
5. Emergence of NDM-1-Producing Pseudomonas aeruginosa Nosocomial Isolates in Attica Region of Greece. Pappa O, Louka C, Karadimas K, …Kyriaki Tryfinopoulou. Microorganisms. 2024 Aug 23;12(9):1753. PMID: 39338428
6. Emergence and persistent spread of carbapenemase-producing Klebsiella pneumoniae high-risk clones in Greek hospitals, 2013 to 2022. Tryfinopoulou K, et al. Euro Surveill. 2023 Nov;28(47):2300571. PMID: 37997662
7. Healthcare-associated infections and antimicrobial use in acute care hospitals in Greece, 2022; results of the third point prevalence survey .Palaiopanos K, et al. Among authors: Tryfinopoulou K. Antimicrob Resist Infect Control. 2024. PMID: 38273402
8. Incidence of SARS-CoV-2 Infection Among European Healthcare Workers and Effectiveness of the First Booster COVID-19 Vaccine, VEBIS HCW Observational Cohort Study, May 2021-May 2023. Savulescu C, et al. Among authors: Tryfinopoulou K. Vaccines (Basel). 2024. PMID: 39591197
9. SARS-CoV-2 seroprevalence among children in Greece during Omicron variant period. Dimopoulou D, et al. Among authors: Tryfinopoulou K. Eur J Pediatr. 2024. PMID: 38478132
10. A Community Waterborne Salmonella Bovismorbificans Outbreak in Greece.
Politi L, et al. Among authors: Tryfinopoulou K. Int J Environ Res Public Health. 2024

11. History repeats itself: consumption of a local traditional roast pork meat recipe leads to Salmonella ser. Give cases in Greece. Mandilara G, et al. Among authors: Tryfinopoulou K. Rural Remote Health. 2024. PMID: 38957085
12. Epidemiology and Resistance Phenotypes of Carbapenem-Resistant Klebsiella pneumoniae in Corfu General Hospital (2019-2022): A Comprehensive Time Series Analysis of Resistance Gene Dynamics. Sorovou G, et al. Among authors: Tryfinopoulou K. Microorganisms. 2023. PMID: 37894196
13. Antimicrobial susceptibility testing and reporting practices of public hospital microbiology laboratories in Greece, 2022: A national observational survey and call for action. Karagiannidou S, et al. Among authors: Tryfinopoulou K. Euro Surveill. 2023. PMID: 37616113
14. Overview of Mpox Outbreak in Greece in 2022-2023: Is It Over? Mellou K, et al. Among authors: Tryfinopoulou K. Viruses. 2023. PMID: 37376683
15. Simultaneous Multiple-Stages Mpox Genital Lesions on the Same Site in a Traveler to Greece: A Case Report. Anna Tagka, Styliani Geronikolou, Apostolos Evaggelopoulos, Sotiria Grigoropoulou, Dimitra Kavatha,Chryssoula Botsi, Aggeliki Papadopoulou, Kyriaki Tryfinopoulou, Antigoni Katsoulidou, Styliani Pappa, Anna Papa, Vasilios Paparizos,Electra Nicolaidou, Sotirios Tsiodras, and Alexandros J. Stratigos. Vaccines (Basel).2023 May; 11(5):901. doi: 10.3390/vaccines11050901

16. Influenza transmission during COVID-19 measures downscaling in Greece, August 2022: evidence for the need of continuous integrated surveillance of respiratory viruses. Mellou K, et al. Among authors: tryfinopoulou k. Euro Surveill. 2023. PMID: 37440348

17. Real life treatment experience and outcome of consecutively hospitalised patients with SARS-CoV-2 pneumonia by Omicron-1 vs Delta variants. Giannitsioti E, et al. Among authors: tryfinopoulou k. Infect Dis (Lond). 2023. PMID: 37427461

18. COVID-19 Burden in Long-Term Care Facilities in the Omicron Era: Public Health Action Not Yet Redundant. Krystallaki D, Kavakioti CA, Gkova M, Sypsa S, Tryfinopoulou K, Gavrili A, Dimitriou A, Sapounas S, Paraskevis D, Mellou K. Viruses. 2023 Mar 14;15(3):752. doi: 10.3390/v15030752. PMID: 36992461

19. Monkeypox virus infection: First reported case in Greece in a patient with a genital rash. Vassilios Paparizos, Electra Nicolaidou, Kyriaki Tryfinopoulou, Anna Papa, Dimitris Rigopoulos, Sotirios Tsiodras, Alexander Stratigos. Journal of The European Academy of Dermatology and Venereology (JEADV) 2022 Aug 14 doi.org/10.1111/jdv.18521

20. Impact of COVID-19 Pandemic on Refugees, Migrants and Asylum Seekers Living in Camps and Reception and Identification Centers in Greece in the Pre-Vaccination Period, February 2020 to May 2021: Summary of Epidemiological Findings. Spiros Sapounas, Konstantinos Mitrou, Alexandros Georgios Asimakopoulos, Garyfallia Antoniou, Ioanna Papari, Anthi Chrysostomou, Ioannis Spyridis, Ioannis Panagoulias, Kassiani Gkolfinopoulou, Grigorios Spanakos, Kyriaki Tryfinopoulou and Kassiani Mellou. J Infect Dis Ther 2022, S6:005

21. COVID-19 and Antimicrobial Resistance: Data from the Greek Electronic System for the Surveillance of Antimicrobial Resistance-WHONET-Greece (January 2018-March 2021).
Polemis M, Mandilara G, Pappa O, Argyropoulou A, Perivolioti E, Koudoumnakis N, Pournaras S, Vasilakopoulou A, Vourli S, Katsifa H, Karampatakis T, Papavasiliou A, Petinaki E, Xitsas S, Skoura L, Protonotariou E, Mantzana P, Gartzonika K, Priavali E, Kallinteri A, Giannopoulou P, Charalampaki N, Memezas M, Calina Oana Z, Papadogianni M, Panopoulou M, Koutsidou A, Vatopoulos A, Tryfinopoulou K. Life (Basel). 2021 Sep 22;11(10):996. doi: 10.3390/life11100996. PMID: 34685368
22. Waterborne outbreak in a rural area in Greece during the COVID-19 pandemic: contribution of community pharmacies.
Mellou K, Sideroglou T, Kefaloudi C, Tryfinopoulou K, Chrysostomou A, Mandilara G, Pavlaki M, Maltezou HC. Rural Remote Health. 2021 Jul;21(3):6630. doi: 10.22605/RRH6630. Epub 2021 Jul 28. PMID: 34320325

23. Public health and clinical implications of multidrug-resistant shigellosis cases in a reception centre for refugees/migrants, Greece, October-December 2019.
Mellou K, Mandilara G, Chrysostomou A, Tryfinopoulou K, Sideroglou T, Karadimas K, Agiassoti VT, Lamprou D, Zampeta E, Antoniou G, Maltezou HC, Panayiotakopoulos G. Eur J Public Health. 2021 Jul 13;31(3):588-590. doi: 10.1093/eurpub/ckaa220. PMID: 33313745

24. The Rising Burden of Salmonellosis Caused by Monophasic Salmonella Typhimurium (1,4,[5],12:i:-) in Greece and New Food Vehicles.
Mandilara G, Sideroglou T, Chrysostomou A, Rentifis I, Papadopoulos T, Polemis M, Tzani M, Tryfinopoulou K, Mellou K. Antibiotics (Basel). 2021 Feb 13;10(2):185. doi: 10.3390/antibiotics10020185. PMID: 33668483

25. Molecular Epidemiology of Multi-Drug Resistant Pseudomonas aeruginosa Isolates from Hospitalized Patients in Greece.
Pappa O, Kefala AM, Tryfinopoulou K, Dimitriou M, Kostoulas K, Dioli C, Moraitou E, Panopoulou M, Vogiatzakis E, Mavridou A, Galanis A, Beloukas A.
Microorganisms. 2020 Oct 24;8(11):1652.

26. Eight-year trends in the relative isolation frequency and antimicrobial susceptibility among bloodstream isolates from Greek hospitals: data from the Greek Electronic System for the Surveillance of Antimicrobial Resistance – WHONET-Greece, 2010 to 2017.
Polemis M, Tryfinopoulou K, Giakkoupi P; WHONET-Greece study group, Vatopoulos A. Euro Surveill. 2020 Aug;25(34):1900516.

27. Evidence for waterborne origin of an extended mixed gastroenteritis outbreak in a town in Northern Greece, 2019.
Tzani M, Mellou K, Kyritsi M, Kolokythopoulou F, Vontas A, Sideroglou T, Chrysostomou A, Mandilara GD, Tryfinopoulou K, Georgakopoulou T, Hadjichristodoulou C. Epidemiol Infect. 2020 Dec 9:1-30
28. A patient with respiratory toxigenic diphtheria in Greece after more than 30 years.
Georgakopoulou T, Tryfinopoulou K, Doudoulakakis A, Nikolaou F, Magaziotou I, Flountzi A, Fry NK, Litt DJ, Damala M, Spiliopoulou I, Liatsi-Douvitsa E, Lebessi E, Panayiotakopoulos G, Tsolia M, Saroglou G, Theodoridou M, Tsiodras S, Efstratiou A. Epidemiol Infect. 2020 Oct 28;148:e274

29. Integrated chromosomal and plasmid sequence analyses reveal diverse modes of carbapenemase gene spread among Klebsiella pneumoniae.
David S, Cohen V, Reuter S, Sheppard AE, Giani T, Parkhill J; Andi Koraqi, Denada Lacej, Petra Apfalter, Rainer Hartl, Youri Glupczynski, Te-Din Huang, Tanya Strateva, Yuliya Marteva-Proevska, Arjana Tambic Andrasevic, Iva Butic, Despo Pieridou-Bagatzouni, Panagiota Maikanti-Charalampous, Jaroslav Hrabak, Helena Zemlickova, Anette Hammerum, Lotte Jakobsen, Marina Ivanova, Anastasia Pavelkovich, Jari Jalava, Monica Österblad, Laurent Dortet, Sophie Vaux, Martin Kaase, Sören G Gatermann, Alkiviadis Vatopoulos, Kyriaki Tryfinopoulou, Ákos Tóth, Laura Jánvári, Teck Wee Boo, Elaine McGrath, Yehuda Carmeli, Amos Adler, Annalisa Pantosti, Monica Monaco, Lul Raka, Arsim Kurti, Arta Balode, Mara Saule, Jolanta Miciuleviciene, Aiste Mierauskaite, Monique Perrin-Weniger, Paul Reichert, Nina Nestorova, Sonia Debattista, Gordana Mijovic, Milena Lopicic, Ørjan Samuelsen, Bjørg Haldorsen, Dorota Żabicka, Elżbieta Literacka, Manuela Caniça, Vera Manageiro, Ana Kaftandzieva, Elena Trajkovska-Dokic, Maria Damian, Brandusa Lixandru, Zora Jelesic, Anika Trudic, Milan Niks, Eva Schreterova, Mateja Pirs, Tjasa Cerar, Jesús Oteo-Iglesias, María Pérez-Vázquez, Christian Giske, Karin Sjöström, Deniz Gür, Aslı Cakar, Neil Woodford, Katie Hopkins, Camilla Wiuff, Derek J Brown, Guido Werner, Natacha CoutoRossolini GM, Feil EJ, Grundmann H, Aanensen DM. Proc Natl Acad Sci U S A. 2020 Oct 6;117(40):25043-25054.

30. Epidemic of carbapenem-resistant Klebsiella pneumoniae in Europe is driven by nosocomial spread.
David, S., Reuter, S., Harris, S.R., Glasner, C., Feltwell, T., Argimon, S., Abudahab, K., Goater, R.,Giani, T., Errico, G., Aspbury, M., Sjunnebo, S., Koraqi, A., Lacej, D., Apfalter, P., Hartl, R.,Glupczynski, Y., Huang, T.-D., Strateva, T., Marteva-Proevska, Y., Andrasevic, A.T., Butic, I.,Pieridou-Bagatzouni, D., Maikanti-Charalampous, P., Hrabak, J., Zemlickova, H., Hammerum, A.,Jakobsen, L., Ivanova, M., Pavelkovich, A., Jalava, J., Österblad, M., Dortet, L., Vaux, S., Kaase, M.,Gatermann, S.G., Vatopoulos, A., Tryfinopoulou, K., Tóth, Á., Jánvári, L., Boo, T.W., McGrath, E.,Carmeli, Y., Adler, A., Pantosti, A., Monaco, M., Raka, L., Kurti, A., Balode, A., Saule, M.,Miciuleviciene, J., Mierauskaite, A., Perrin-Weniger, M., Reichert, P., Nestorova, N., Debattista, S.,
Mijovic, G., Lopicic, M., Samuelsen, Ø., Haldorsen, B., Zabicka, D., Literacka, E., Caniça, M.,Manageiro, V., Kaftandzieva, A., Trajkovska-Dokic, E., Damian, M., Lixandru, B., Jelesic, Z., Trudic,A., Niks, M., Schreterova, E., Pirs, M., Cerar, T., Oteo, J., Aracil, B., Giske, C., Sjöström, K., Gür, D.,Cakar, A., Woodford, N., Hopkins, K., Wiuff, C., Brown, D.J., Feil, E.J., Rossolini, G.M., Aanensen,D.M., Grundmann, H. Nat Microbiol. 2019 Nov;4(11):1919-1929.
Αναφορές: 299 (Google Scholar), 271 (Scopus)

31. Synergistic activity of colistin with azidothymidine against colistin-resistant Klebsiella pneumoniae clinical isolates collected from inpatients in Greek hospitals
Falagas ME, Voulgaris GL, Tryfinopoulou K, Giakkoupi P, Kyriakidou M, Vatopoulos A, Coates A, Hu Y; Colistin – Azidothymidine Hellenic Study Group. Int J Antimicrob Agents. 2019 Jun; 53(6):855-85

32. Norovirus waterborne outbreak in Chalkidiki, Greece, 2015: detection of GI.P2_GI.2 and GII.P16_GII.13 unusual strains.
Tryfinopoulou K, Kyritsi M, Mellou K, Kolokythopoulou F, Mouchtouri VA, Potamiti-Komi M, Lamprou A, Georgakopoulou T, Hadjichristodoulou C. Epidemiol Infect. 2019 Jan;147:e227
33. Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational study
Grundmann, H., Glasner, C., Albiger, B., Aanensen, D.M., Tomlinson, C.T., Andrasević, A.T., Cantón,R., Carmeli, Y., Friedrich, A.W., Giske, C.G., Glupczynski, Y., Gniadkowski, M., Livermore, D.M.,Nordmann, P., Poirel, L., Rossolini, G.M., Seifert, H., Vatopoulos, A., Walsh, T., Woodford, N.,Monnet, D.L., Apfalter, P., Hartl, R., Glupczynski, Y., Huang, T.-D., Strateva, T., Marteva-Proevska,Y., Andraševic, A.T., Butic, I., Pieridou-Bagatzouni, D., Maikanti-Charalampous, P., Hrabak, J.,Zemlickova, H., Hammerum, A., Jakobsen, L., Ivanova, M., Pavelkovich, A., Jalava, J., Österblad, M.,Vaux, S., Dortet, L., Kaase, M., Gatermann, S.G., Vatopoulos, A., Tryfinopoulou, K., Tóth, Á., Jánvári,L., Boo, T.W., McGrath, E., Pantosti, A., Monaco, M., Balode, A., Saule, M., Miciuleviciene, J.,Mierauskaite, A., Perrin-Weniger, M., Reichert, P., Nestorova, N., Debattista, S., Zabicka, D.,Literacka, E., Caniça, M., Manageiro, V., Damian, M., Lixandru, B., Nikš, M., Schreterova, E., Pirš,M., Cerar, T., Oteo, J., Aracil, B., Giske, C.G., Sjöström, K., Woodford, N., Hopkins, K., Wiuff, C.,Brown, D.J., Hardarson, H., Samuelsen, Ø., Haldorsen, B., Koraqi, A., Lacej, D., Raka, L., Kurti, A.,Mijovic, G., Lopicic, M., Jelesic, Z., Trudic, A., Kraftandzieva, A., Trajkovska-Dokic, E., Gür, D.,Cakar, A., Carmeli, Y., Adler, A. Lancet Infect Dis. 2017 Feb;17(2):153-163.

34. Antiviral susceptibility profile of influenza A viruses; keep an eye on immunocompromised patients under prolonged treatment.
Kossyvakis A, Mentis AA, Tryfinopoulou K, Pogka V, Kalliaropoulos A, Antalis E, Lytras T, Meijer A, Tsiodras S, Karakitsos P, Mentis AF. Eur J Clin Microbiol Infect Dis. 2017 Feb;36(2):361-371.
35. Meningococcal Carriage in Military Recruits and University Students during the Pre MenB Vaccination Era in Greece (2014-2015). Tryfinopoulou K, Kesanopoulos K, Xirogianni A, Marmaras N, Papandreou A,Papaevangelou V, Tsolia M, Jasir A, Tzanakaki G. PLoS One. 2016 Dec 1;11(12)
36. Resistant Shigella strains in refugees, August-October 2015, Greece.
Georgakopoulou T, Mandilara G, Mellou K, Tryfinopoulou K, Chrisostomou A, Lillakou H, Hadjichristodoulou C, Vatopoulos A. Epidemiol Infect. 2016 Aug;144(11):2415-9.

37. Influenza vaccine effectiveness in preventing hospitalizations with laboratory-confirmed influenza in Greece during the 2014-2015 season: A test-negative study.
Lytras T, Kossyvakis A, Melidou A, Andreopoulou A, Exindari M, Gioula G, Kalliaropoulos A, Tryfinopoulou K, Pogka V, Spala G, Malisiovas N, Mentis A. J Med Virol. 2016 Nov;88(11):1896-904

38. Cave cyanobacteria showing antibacterial activity.
Lamprinou V, Tryfinopoulou K, Velonakis EN, Vatopoulos A, Antonopoulou S, Fragopoulou E, Pantazidou A, Economou-Amilli A. Int J Speleology. 2015 Sept;44(3): 231-238

39. Circulation of a multiresistant, conjugative, IncA/C plasmid within the nosocomial Providencia stuartii population in the Athens area.
Giakkoupi P, Tryfinopoulou K, Polemis M, Pappa O, Miriagou V, Vatopoulos A. Diagn Microbiol Infect Dis. 2015 May;82(1):62-4.

40. MgrB inactivation is a common mechanism of colistin resistance in KPC carbapenemase-producing Klebsiella pneumoniae of clinical origin.
Cannatelli A, Giani T, D’Andrea MM, Di Pilato V, Arena F, Conte V, Tryfinopoulou K; the COLGRIT Study Group, Vatopoulos A, Rossolini GM.

41. Emergence of NDM-producing Klebsiella pneumoniae in Greece.
Giakkoupi P, Tryfinopoulou K, Kontopidou F, Tsonou P, Golegou T, Souki H, Tzouvelekis L, Miriagou V, Vatopoulos A Microbiol Diagn Infect Dis. 2013 Dec;77(4):382-4.

42. Outbreak of pan-susceptible Klebsiella pneumoniae in a neonatal intensive care unit.
Maltezou HC, Papacharalambous E, Tryfinopoulou K, Ftika L, Maragos A, Kyriakeli G, Katerelos P, Trakateli C, Polemis M, Roilides E, Vatopoulos A, Nikolaidis N. Scand J Infect Dis. 2013 Nov;45(11):872-7

43. Consecutive Serratia marcescens multiclone outbreaks in a neonatal intensive care unit.
Maltezou HC, Tryfinopoulou K, Katerelos P, Ftika L, Pappa O, Tseroni M, Kostis E, Kostalos C, Prifti H, Tzanetou K, Vatopoulos A. Am J Infect Control. 2012 Sep; 40(7):637-42.

44. Diversity of acquired β-lactamases amongst Klebsiella pneumoniae in Greek hospitals.
Papagiannitsis CC, Tryfinopoulou K, Giakkoupi P, Pappa O, Polemis M, Tzelepi E, Tzouvelekis LS; Carbapenemase Study Group, Vatopoulos AC.Int J Antimicrob Agents. 2012 Feb;39(2):178-80

45. Burkholderia cenocepacia bacteremia without respiratory colonization in an adult intensive care unit: epidemiological and molecular investigation of an outbreak Katsiari M, Roussou Z, Tryfinopoulou K, Vatopoulos AC , Platsouka ED, Maguina A, Hippokratia 2012, 14, 4: 317-323

46. An update of the evolving epidemic of blaKPC-2-carrying Klebsiella pneumoniae in Greece (2009-10).
Giakkoupi P, Papagiannitsis CC, Miriagou V, Pappa O, Polemis M, Tryfinopoulou K, Tzouvelekis LS, Vatopoulos AC. J Antimicrob Chemother. 2011 Jul; 66(7):1510-3

47. Emergence of Klebsiella pneumoniae of a new sequence type (ST383) producing VIM-4, KPC-2 and CMY-4 β-lactamases
Papagiannitsis CC, Giakkoupi P, Vatopoulos AC, Tryfinopoulou K, Miriagou V, Tzouvelekis LS.Int J Antimicrob Agents. 2010 Dec; 36(6):573-4.

48. Serologic markers of persistent Chlamydia pneumonia infection and long-term prognosis after successful coronary stenting. American Heart Journal, December 2003, Volume 146, Issue 6, Pages 1082-1089
Michael N. Zairis MD, Olga A. Papadaki MD, Paraskevi K. Psarogianni MD, Maria A. Thoma MD, George K. Andrikopoulos MD, Pelagia C. Batica RN, Christina G. Poulopoulou MD, Kyriaki G. Tryfinopoulou MD, Christopher D. Olympios MD, and Stefanos G. Fousas MD, FESC, FACC

Γενική Γραμματέας του ΔΣ της Εταιρείας Κλινικής Μικροβιολογίας και Εργαστηριακής Διαγνωστικής (ΕΚΜΕΔ) • Γενική Γραμματέας του ΔΣ της Ελληνικής Εταιρείας Βιοασφάλειας • Μέλος της Ελληνικής Μικροβιολογικής Εταιρείας • Μέλος της European Society of Clinical Microbiology and Infectious Diseases (ESCMID) • Mέλος 9 ομάδων εργασίας (study groups) του ESCMID o Biofilms, Bloodstream Infections, C.difficile, Epi Markers, Food and Water-borne Diseases, Genomics & Molecular diagnostics, Nosocomial Infections, Public Health Microbiology and Resistance surveillance