Sourvinos George

– Herpesviruses and cell-host interactions
– Moleculal diagnostics in Clinical Virology
– Genomic surveillance of viral genome
– Surveillance of respiratory virusus, HIV, HPV
– Public Health

Selected Publications

Leruez-Ville M, Chatzakis C, Lilleri D, Blazquez-Gamero D, Alarcon A, Bourgon N, Foulon I, Fourgeaud J, Gonce A, Jones CE, Klapper P, Krom A, Lazzarotto T, Lyall H, Paixao P, Papaevangelou V, Puchhammer E, SOURVINOS G, Vallely P, Ville Y, Vossen A. Consensus recommendation for prenatal, neonatal and postnatal management of congenital cytomegalovirus infection from the European congenital infection initiative (ECCI). Lancet Reg Health Eur. 2024 Apr 1;40:100892.

Alarifi S, Alkahtani S, Al-Qahtani AA, Stournaras C, SOURVINOS G. Induction of interleukin-11 mediated by RhoA GTPase during human cytomegalovirus lytic infection. Cell Signal 70:109599, 2020.

Paraskevis D, Kostaki EG, Magiorkinis G, Panayiotakopoulos G, SOURVINOS G, Tsiodras S. Full-genome evolutionary analysis of the novel corona virus (2019-nCoV) rejects the hypothesis of emergence as a result of a recent recombination event. Infect Genet Evol 79:104212, 2020.

M. Tseliou, S.A. Pirintsos, C. Lionis, E. Castanas, G. SOURVINOS. Antiviral effect of an essential oil combination derived from three aromatic plants (Coridothymus capitatus (L.) Rchb. f., Origanum dictamnus L. and Salvia fruticosa Mill.) against viruses causing infections of the upper respiratory tract. Journal of Herbal Medicine 17–18, 2019.

Goulidaki N, Alarifi S, Alkahtani SH, Al-Qahtani A, Spandidos DA, Stournaras C, SOURVINOS G. RhoB is a component of the human cytomegalovirus assembly complex and is required for efficient viral production. Cell Cycle, 14:2748-2763, 2016.

V.M. Vlahava, A.G. Eliopoulos, G. SOURVINOS. CD40 ligand exhibits a direct antiviral effect on Herpes Simplex Virus type-1 infection via a PI3K-dependent, autophagy-independent mechanism. Cellular Signalling, 27:1253-1263, 2015.

G. SOURVINOS, A. Morou, I. Sanidas, I. Codruta, S.A. Ezell, C. Doxaki, Sotirios C. Kampranis, F. Kottakis and P.N. Tsichlis. The downregulation of GFI1 by the EZH2-NDY1/KDM2B-JARID2 axis and by human cytomegalovirus (HCMV) associated factors allows the activation of the HCMV major IE promoter and the transition to productive infection. PLoS Pathogens, 10(5):e1004136, 2014.

Lasithiotaki I, Antoniou KM, Derdas SP, Sarchianaki E, Symvoulakis EK, Psaraki A, Spandidos DA, Stathopoulos EN, Siafakas NM, SOURVINOS G. The presence of Merkel cell polyomavirus is associated with deregulated expression of BRAF and Bcl-2 genes in non-small cell lung cancer. International Journal of Cancer, 133: 604-611, 2013.

S.A. Ezell, C. Polytarchou, M. Hatziapostolou, A. Guo, I. Sanidas, T. Bihani, M.J. Comb, G. SOURVINOS, P.N. Tsichlis. Akt1 regulates the interferon response and viral replication through phosphorylation of the transcriptional repressor EMSY. Proc Natl Acad Sci USA, 109: E613-21, 2012.

C. Filippakis, P. Dimitropoulou, A.G. Eliopoulos, D.A Spandidos, G. SOURVINOS. The enhanched host-cell permissivenes of Human Cytomegalovirus is mediated by the Ras signalling pathway. Biochimica et Biophysica Acta-Molecular Cell Research, 1813: 1872-1882, 2011.

G. Dimitropoulou, R. Caswell, B.P. McSharry, R.F. Greaves, G.W. Wilkinson, D.A. Spandidos, G SOURVINOS. Differential relocation and stability of PML-body components during productive Human Cytomegalovirus infection; Detailed characterization by live cell imaging. European Journal of Cell Biology, 89: 757-768, 2010.

G SOURVINOS, N Tavalai, A Berndt, D.A. Spandidos and Thomas Stamminger. Recruitment of human cytomegalovirus immediate early 2 protein IE86 onto parental viral genomes in association with ND10 in live infected cells. Journal of Virology, 81: 101123-10136, 2007.

Executive Board Member European Society for Clinical Virology
Member of Hellenic Society for Clinical Virology
Advisory Board Member, European Society of Virology
Associate Editor, Journal of Clinical Virology